Also consider the work done by John Young of the USGS. He had a graphic which showed three overarching genotypes of ginseng. One along the eastern side of the Appalachians, one along the western side, and one along the Ohio River valley. Add to this work done by folks like Dave Devinny, who posit that ginseng genetics currently suggest the possibility of one -or very few- very large populations covering many thousands of square miles geographically. With the increase of deer predation, and loss of habitat, populations were broken up and became geographically isolated. Because of the selfing nature of ginseng, these local populations begin to specialize if you will in their local environments. For instance, a patch of a dozen plants on this side of the hill might be genetically different from a dozen plants in a patch on the other side of the same hill less than a half mile away. Mind you, these differences are really not that much different at all to us.
As for the source of seed, all ginseng plants originated from wild stock. That some of the seeds from commercially grown plants find their way back into the woods in my mind -and in my experience- does not make the resulting plants cultivated. Are there genetic differences? Almost certainly their are. However, just because you find a seed dealer near you, doesn't mean his or her seeds are not from commercial sources. Nearly all if not all of the seed available in any quantity on the market originates from cultivated fields. It is just too time consuming to actually harvest seeds economically from true wild or wild simulated operations.
I was working on a project on this topic early in the year, but as the year has progressed, I've had to leave it sit for the time being until my time frees up once again.